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KMID : 1103720170770040229
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Journal of the Korean Society of Radiology
2017 Volume.77 No. 4 p.229 ~ p.236
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Liver Abscess Formation after Radiofrequency Ablation of Hepatocellular Carcinoma
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Kim Ju-Won
Kim Mi-Young
Cho Yun-Ku
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Abstract
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Purpose: To determine prognostic factors for the development of liver abscess formation in patients with hepatocellular carcinoma (HCC) treated with radiofrequency ablation (RFA) focusing on the history of multiple prior sessions of transarterial chemoembolization (TACE).
Materials and Methods: Patients were included if RFA was performed from January 2005 to July 2016 for a single HCC nodule smaller than or equal to 5 cm or up to three nodules with each nodule smaller than or equal to 3 cm. Univariate and multivariate logistic regression analyses were conducted and propensity score matching was performed between those without multiple prior sessions of TACE before ablation (Group 1) and those with such a history (Group 2).
Results: Overall, 694 patients were included in this study. Liver abscesses were developed in four patients, all in Group 2. After performing 2:1 propensity score matching, 149 and 81 patients were selected for Group 1 and 2, respectively. Among these matched patients, rates of liver abscess development were 0% and 5.1% in Group 1 and 2, respectively. The difference in rate of liver abscess development between the two groups was statistically significant (p = 0.014).
Conclusion: A history of multiple prior TACE sessions was a potent predictor for liver abscess formation in patients with HCC after performing RFA.
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KEYWORD
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Liver, Hepatocellular Carcinoma, Catheter Ablation, Abscess, Therapeutic Chemoembolization
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